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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HRH1
All Species:
6.36
Human Site:
S344
Identified Species:
10.77
UniProt:
P35367
Number Species:
13
Phosphosite Substitution
Charge Score:
0.23
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P35367
NP_000852.1
487
55784
S344
G
L
N
T
H
G
A
S
E
I
S
E
D
Q
M
Chimpanzee
Pan troglodytes
Q9N2B2
487
55605
S344
G
L
N
T
H
G
A
S
E
I
S
E
D
Q
M
Rhesus Macaque
Macaca mulatta
P56490
532
60122
A368
Y
F
L
S
P
A
A
A
H
R
P
K
S
Q
K
Dog
Lupus familis
XP_541769
536
61594
N393
G
L
N
M
R
G
A
N
E
T
S
E
D
Q
I
Cat
Felis silvestris
Mouse
Mus musculus
P70174
488
55663
E345
S
T
C
R
R
I
S
E
T
S
E
D
Q
T
L
Rat
Rattus norvegicus
P31390
486
55674
E343
N
T
C
R
R
I
S
E
T
S
E
D
Q
T
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505379
489
54959
D346
P
A
T
L
E
P
S
D
T
S
D
E
H
T
F
Chicken
Gallus gallus
P30372
466
51547
Q335
I
R
I
V
T
K
S
Q
K
G
D
C
C
A
P
Frog
Xenopus laevis
P30544
484
54107
E352
V
T
K
Q
T
G
N
E
C
V
T
A
I
E
I
Zebra Danio
Brachydanio rerio
NP_001036196
534
61056
G391
V
L
V
P
N
S
V
G
N
I
C
E
S
A
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q8IS44
506
56459
L384
L
A
R
N
D
S
T
L
S
T
T
S
K
T
S
Honey Bee
Apis mellifera
XP_395477
546
60788
H400
P
V
F
S
T
N
G
H
L
N
G
I
Q
S
A
Nematode Worm
Caenorhab. elegans
Q18775
517
58629
T358
I
G
S
N
C
S
S
T
L
L
Q
V
D
Q
P
Sea Urchin
Strong. purpuratus
NP_001012721
677
76342
R506
K
T
T
S
P
K
Y
R
G
V
R
Y
N
K
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.7
27
78.5
N.A.
78
78.8
N.A.
60.1
27.3
27.7
41.3
N.A.
28.6
28.3
26.8
29.2
Protein Similarity:
100
99.1
44.7
83.4
N.A.
84.6
85.6
N.A.
70.7
47.2
44.5
57.1
N.A.
48.8
43
46.8
49
P-Site Identity:
100
100
13.3
66.6
N.A.
0
0
N.A.
6.6
0
6.6
20
N.A.
0
0
13.3
0
P-Site Similarity:
100
100
33.3
80
N.A.
20
20
N.A.
13.3
13.3
33.3
26.6
N.A.
6.6
13.3
40
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
15
0
0
0
8
29
8
0
0
0
8
0
15
8
% A
% Cys:
0
0
15
0
8
0
0
0
8
0
8
8
8
0
0
% C
% Asp:
0
0
0
0
8
0
0
8
0
0
15
15
29
0
0
% D
% Glu:
0
0
0
0
8
0
0
22
22
0
15
36
0
8
8
% E
% Phe:
0
8
8
0
0
0
0
0
0
0
0
0
0
0
8
% F
% Gly:
22
8
0
0
0
29
8
8
8
8
8
0
0
0
0
% G
% His:
0
0
0
0
15
0
0
8
8
0
0
0
8
0
0
% H
% Ile:
15
0
8
0
0
15
0
0
0
22
0
8
8
0
15
% I
% Lys:
8
0
8
0
0
15
0
0
8
0
0
8
8
8
8
% K
% Leu:
8
29
8
8
0
0
0
8
15
8
0
0
0
0
15
% L
% Met:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
15
% M
% Asn:
8
0
22
15
8
8
8
8
8
8
0
0
8
0
0
% N
% Pro:
15
0
0
8
15
8
0
0
0
0
8
0
0
0
22
% P
% Gln:
0
0
0
8
0
0
0
8
0
0
8
0
22
36
0
% Q
% Arg:
0
8
8
15
22
0
0
8
0
8
8
0
0
0
0
% R
% Ser:
8
0
8
22
0
22
36
15
8
22
22
8
15
8
8
% S
% Thr:
0
29
15
15
22
0
8
8
22
15
15
0
0
29
0
% T
% Val:
15
8
8
8
0
0
8
0
0
15
0
8
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
8
0
0
0
0
0
8
0
0
0
0
8
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _